Journal article
The apicoplast genomes of two taxonomic units of Babesia from sheep
T Wang, G Guan, PK Korhonen, AV Koehler, RS Hall, ND Young, H Yin, RB Gasser
Veterinary Parasitology | ELSEVIER SCIENCE BV | Published : 2017
Abstract
The apicoplast (ap) is a unique, non-photosynthetic organelle found in most apicomplexan parasites. Due to the essential roles that this organelle has, it has been widely considered as target for drugs against diseases caused by apicomplexans. Exploring the ap genomes of such parasites would provide a better understanding of their systematics and their basic molecular biology for therapeutics. However, there is limited information available on the ap genomes of apicomplexan parasites. In the present study, the ap genomes of two operational taxonomic units of Babesia (known as Babesia sp. Lintan [Bl] and Babesia sp. Xinjiang [Bx]) from sheep were sequenced, assembled and annotated using a mas..
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Grants
Awarded by Alexander von Humboldt-Stiftung
Funding Acknowledgements
This project was partially funded by the PiroVac (KBBE-3-245145; HY), NSFC (31072130; GG), ASTIP, FRIP (2014ZL010), CAAS (HY) and NBCIS (CARS-38; HY) of China and the Australian Research Council (ARC) (RBG); it was also supported by a Victorian Life Sciences Computation Initiative (VLSCI) grant (VR0007; RBG) on its Peak Computing Facility at the University of Melbourne, an initiative of the Victorian Government. Other support from the State Key Laboratory of Veterinary Etiological Biology Project, China (SKLVEB2008ZZKT019; HY), and the University of Melbourne, Australian Academy of Science, Alexander von Humboldt Foundation and Melbourne Water Corporation (RBG) is gratefully acknowledged. NDY is an NHMRC Career Development Fellow.